Location: Model of Human Jejunal Smooth Muscle Cell Electrophysiology @ b98a10f69ee7 / Experiments / Patch_clamp_protocol.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-07-06 11:22:35+12:00
Desc:
Change the figures size to fit the Physiome paper; Adjust the solver setting to remove the notch in Fig6. Minor editting in README.
Permanent Source URI:
https://staging.physiomeproject.org/workspace/692/rawfile/b98a10f69ee76a70243efdb648c598db5a866a2c/Experiments/Patch_clamp_protocol.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="Patch_clamp_protocol" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <!-- clamp the voltage for the activation behaviour-->
    <import xlink:href="../Components/units.cellml">
        <units name="ms" units_ref="ms"/>
        <units name="mV" units_ref="mV"/>
    </import>
    <component name="Patch_clamp_protocol">
        <variable name="V" public_interface="out" units="mV"/>
        <variable name="time" public_interface="in" units="ms"/>
        <variable cmeta:id="steady_state_time" name="t_ss" public_interface="in" units="ms"/>
        <variable cmeta:id="activation_holding_potential" name="V_actHolding" public_interface="in" units="mV"/>
        <variable cmeta:id="activation_test_potential" name="V_actTest" public_interface="in" units="mV"/>
        <!--get the model to steady state at the holding potential.-->
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply id="activation_protocol_clamping">
                <eq/>
                <ci>V</ci>
                <piecewise>
                    <piece>
                        <ci>V_actHolding</ci>
                        <apply>
                            <lt/>
                            <ci>time</ci>
                            <ci>t_ss</ci>
                        </apply>
                    </piece>
                    <otherwise>
                        <ci>V_actTest</ci>
                    </otherwise>
                </piecewise>
            </apply>
        </math>
    </component>
</model>